Whois & Analysis for otezla.com

Apremilast (brand name Otezla) is a medication for the treatment of certain types of psoriasis and psoriatic arthritis.

It may also be useful for other immune system related inflammatory diseases.

The drug acts as a selective inhibitor of the enzyme phosphodiesterase 4 (PDE4) and inhibits spontaneous production of TNF-alpha from human rheumatoid synovial cells.

It is taken by mouth.

Psoriasis is a long-lasting autoimmune disease which is characterized by patches of abnormal skin.

These skin patches are typically red, itchy, and scaly.

They may vary in severity from small and localized to complete body coverage.

Injury to the skin can trigger psoriatic skin changes at that spot, which is known as the Koebner phenomenon.

A pharmaceutical drug (also referred to as medicine, medication, or simply as drug) is a drug used to diagnose, cure, treat, or prevent disease.

Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management.

A tablet is a pharmaceutical dosage form.

Tablets may be defined as the solid unit dosage form of medicament or medicaments with or without suitable excipients and prepared either by molding or by compression.

It comprises a mixture of active substances and excipients, usually in powder form, pressed or compacted from a powder into a solid dose.

The excipients can include diluents, binders or granulating agents, glidants (flow aids) and lubricants to ensure efficient tabletting; disintegrants to promote tablet break-up in the digestive tract; sweeteners or flavours to enhance taste; and pigments to make the tablets visually attractive or aid in visual.

A polymer coating is often applied to make the tablet smoother and easier to swallow, to control the release rate of the active ingredient, to make it more resistant to the environment (extending its shelf life), or to enhance the tablet's appearance.