Whois & Analysis for omim.org

The genotype is the part (DNA sequence) of the genetic makeup of a cell, and therefore of an organism or individual, which determines a specific characteristic (phenotype) of that cell/organism/individual.

Genotype is one of three factors that determine phenotype, the other two being inherited epigenetic factors, and non-inherited environmental factors.

DNA mutations which are acquired rather than inherited, such as cancer mutations, are not part of the individual's genotype; hence, scientists and physicians sometimes talk for example about the (geno)type of a particular cancer, that is the genotype of the disease as distinct from the diseased.

A phenotype is the composite of an organism's observable characteristics or traits, such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior (such as a bird's nest).

A phenotype results from the expression of an organism's genetic code, its genotype, as well as the influence of environmental factors and the interactions between the two.

When two or more clearly different phenotypes exist in the same population of a species, the species is called polymorphic.

A well-documented polymorphism is Labrador Retriever coloring; while the coat color depends on many genes, it is clearly seen in the environment as yellow, black and brown.

Online Mendelian Inheritance in Man (OMIM) is a continuously updated catalog of human genes and genetic disorders and traits, with a particular focus on the gene-phenotype relationship., approximately 8,425 of the over 23,000 entries in OMIM represented phenotypes; the rest represented genes, many of which were related to known phenotypes.

Genetics is the study of genes, genetic variation, and heredity in living organisms.

It is generally considered a field of biology, but intersects frequently with many other life sciences and is strongly linked with the study of information systems.

A disease is a particular abnormal condition, a disorder of a structure or function, that affects part or all of an organism.

The study of disease is called pathology which includes the study of cause.

Disease is often construed as a medical condition associated with specific symptoms and signs.

It may be caused by external factors such as pathogens, or it may be caused by internal dysfunctions particularly of the immune system such as an immunodeficiency, or a hypersensitivity including allergies and autoimmunity.