Whois & Analysis for tandemdiabetes.com

Insulin (from the Latin, insula meaning island) is a peptide hormone produced by beta cells of the pancreatic islets.

It regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of, especially, glucose from the blood into fat, liver and skeletal muscle cells.

In these tissues the absorbed glucose is converted into either glycogen via glycogenesis or fats (triglycerides) via lipogenesis, or, in the case of the liver, into both.

Glucose production (and excretion into the blood) by the liver is strongly inhibited by high concentrations of insulin in the blood.

Circulating insulin also affects the synthesis of proteins in a wide variety of tissues.

It is therefore an anabolic hormone, promoting the conversion of small molecules in the blood into large molecules inside the cells.

Low insulin levels in the blood have the opposite effect by promoting widespread catabolism.

The term diabetes includes several different metabolic disorders that all, if left untreated, result in abnormally high concentration of a sugar called glucose in the blood.

Diabetes mellitus type 1 results when the pancreas no longer produces significant amounts of the hormone insulin, usually owing to the autoimmune destruction of the insulin-producing beta cells of the pancreas.

Diabetes mellitus type 2, in contrast, is now thought to result from autoimmune attacks on the pancreas and/or insulin resistance.

The pancreas of a person with type 2 diabetes may be producing normal or even abnormally large amounts of insulin.

Other forms of diabetes mellitus, such as the various forms of maturity onset diabetes of the young, may represent some combination of insufficient insulin production and insulin resistance.

Some degree of insulin resistance may also be present in a person with type 1 diabetes.