Whois & Analysis for twistdna.com

Synthetic biology is an interdisciplinary branch of biology and engineering.

The subject combines various disciplines from within these domains, such as biotechnology, evolutionary biology, genetic engineering, molecular biology, molecular engineering, systems biology, biophysics, and computer engineering.

Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics.

Commonly made in the laboratory by solid-phase chemical synthesis, these small bits of nucleic acids can be manufactured as single-stranded molecules with any user-specified sequence, and so are vital for artificial gene synthesis, polymerase chain reaction (PCR), DNA sequencing, library construction and as molecular probes.

In nature, oligonucleotides are usually found as small RNA molecules that function in the regulation of gene expression (e.g. microRNA), or are degradation intermediates derived from the breakdown of larger nucleic acid molecules.

Artificial gene synthesis, sometimes known as DNA printing is a method in synthetic biology that is used to create artificial genes in the laboratory.

Currently based on solid-phase DNA synthesis, it differs from molecular cloning and polymerase chain reaction (PCR) in that the user does not have to begin with preexisting DNA sequences.

Therefore, it is possible to make a completely synthetic double-stranded DNA molecule with no apparent limits on either nucleotide sequence or size.

The method has been used to generate functional bacterial or yeast chromosomes containing approximately one million base pairs.

Recent research also suggests the possibility of creating novel nucleobase pairs in addition to the two base pairs in nature, which could greatly expand the genetic code.

In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.

This process occurs in all living organisms and is the basis for biological inheritance.

DNA is made up of a double helix of two complementary strands.

During replication, these strands are separated.

Each strand of the original DNA molecule then serves as a template for the production of its counterpart, a process referred to as semiconservative replication.

Cellular proofreading and error-checking mechanisms ensure near perfect fidelity for DNA replication.

Biotechnology is the use of living systems and organisms to develop or make products, or "any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use" (UN Convention on Biological Diversity, Art.

2).

Depending on the tools and applications, it often overlaps with the (related) fields of bioengineering, biomedical engineering, biomanufacturing, molecular engineering, etc.