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Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle.

The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw.

Often it is in the center or left side of the chest and lasts for more than a few minutes.

The discomfort may occasionally feel like heartburn.

Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired.

About 30% of people have atypical symptoms, with women more likely than men to present atypically.

Among those over 75 years old, about 5% have had an MI with little or no history of symptoms.

An MI may cause heart failure, an irregular heartbeat (including serious types), cardiogenic shock, or cardiac arrest.

Drugs used in diabetes treat diabetes mellitus by lowering glucose levels in the blood.

With the exceptions of insulin, exenatide, liraglutide and pramlintide, all are administered orally and are thus also called oral hypoglycemic agents or oral antihyperglycemic agents.

There are different classes of anti-diabetic drugs, and their selection depends on the nature of the diabetes, age and situation of the person, as well as other factors.

A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue, causes a physiological change in the body.

Clinical trials are experiments or observations done in clinical research.

Such prospective biomedical or behavioral research studies on human participants are designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison.

Clinical trials generate data on safety and efficacy.

They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought.

These authorities are responsible for vetting the risk/benefit ratio of the trial – their approval does not mean that the therapy is 'safe' or effective, only that the trial may be conducted.

A patient is any recipient of health care services.

The patient is most often ill or injured and in need of treatment by a advanced practice registered nurse, physiotherapist, physician, physician assistant, psychologist, podiatrist, veterinarian, or other health care provider.